Pyrogenic and neuroinflammatory properties of zymosan and its potential as an alternative to live yeast in antipyretic drug testing
Zymosan, an immunogenic cell wall extract of Saccharomyces cerevisiae has potential for use as an experimental pyrogen. However, the short-lived sickness responses noted with intraperitoneal and intra-articular administration of zymosan limits investigations on the long-term effectiveness of antipyr...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Canadian Science Publishing
2019-05-01
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| Series: | FACETS |
| Subjects: | |
| Online Access: | https://www.facetsjournal.com/doi/10.1139/facets-2018-0045 |