Immune regulation by protein ubiquitination: roles of the E3 ligases VHL and Itch

Immune regulation by protein ubiquitination: roles of the E3 ligases VHL and Itch

ABSTRACT Protein ubiquitination is an important means of post-translational modification which plays an essential role in the regulation of various aspects of leukocyte development and function. The specificity of ubiquitin tagging to a protein substrate is determined by E3 ubiquitin ligases via def...

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Bibliographic Details
Main Authors: Daisuke Aki, Qian Li, Hui Li, Yun-Cai Liu, Jee Ho Lee
Format: Article
Language:English
Published: SpringerOpen 2018-11-01
Series:Protein & Cell
Subjects:
ubiquitin
E3 ligase
VHL
HIF
Itch
WWP2
Online Access:http://link.springer.com/article/10.1007/s13238-018-0586-8

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http://link.springer.com/article/10.1007/s13238-018-0586-8

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