Comparison of non-myeloablative lymphodepleting preconditioning regimens in patients undergoing adoptive T cell therapy

Background Adoptive cell therapy with T cells genetically engineered to express a chimeric antigen receptor (CAR-T) or tumor-infiltrating T lymphocytes (TIL) demonstrates impressive clinical results in patients with cancer. Lymphodepleting preconditioning prior to cell infusion is an integral part o...

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Bibliographic Details
Main Authors: Ronnie Shapira-Frommer, Elad Jacoby, Orit Itzhaki, Abraham Nissani, Gal Markel, Jacob Schachter, Shaked Lev-Ari, Tomer Meirson, Nethanel Asher, Guy Ben-Betzalel, Michal J. Besser
Format: Article
Language:English
Published: BMJ Publishing Group 2021-05-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/9/5/e001743.full