Physiological Concentration of Exogenous Lactate Reduces Antimycin A Triggered Oxidative Stress in Intestinal Epithelial Cell Line IPEC-1 and IPEC-J2 In Vitro.

Weaning triggers an adaptation of the gut function including luminal lactate generation by lactobacilli, depending on gastrointestinal site. We hypothesized that both lactobacilli and lactate influence porcine intestinal epithelial cells. In vivo experiments showed that concentration of lactate was...

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Main Authors: Stefan Kahlert, Sami Junnikkala, Lydia Renner, Ulla Hynönen, Roland Hartig, Constanze Nossol, Anikó Barta-Böszörményi, Sven Dänicke, Wolfgang-Bernhard Souffrant, Airi Palva, Hermann-Josef Rothkötter, Jeannette Kluess
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4824430?pdf=render