Synergistic Impairment of the Neurovascular Unit by HIV-1 Infection and Methamphetamine Use: Implications for HIV-1-Associated Neurocognitive Disorders

Synergistic Impairment of the Neurovascular Unit by HIV-1 Infection and Methamphetamine Use: Implications for HIV-1-Associated Neurocognitive Disorders

The neurovascular units (NVU) are the minimal functional units of the blood–brain barrier (BBB), composed of endothelial cells, pericytes, astrocytes, microglia, neurons, and the basement membrane. The BBB serves as an important interface for immune communication between the brain and peripheral cir...

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Bibliographic Details
Main Authors: Nikolai Fattakhov, Silvia Torices, Michael Stangis, Minseon Park, Michal Toborek
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Viruses
Subjects:
HIV
methamphetamine
neurovascular unit
HIV-associated neurocognitive disorder
blood–brain barrier
neuroinflammation
Online Access:https://www.mdpi.com/1999-4915/13/9/1883

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https://www.mdpi.com/1999-4915/13/9/1883

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