7,8-Dihydroxyflavone Attenuates Alcohol-Related Behavior in Rat Models of Alcohol Consumption via TrkB in the Ventral Tegmental Area

7,8-Dihydroxyflavone Attenuates Alcohol-Related Behavior in Rat Models of Alcohol Consumption via TrkB in the Ventral Tegmental Area

Alcohol use disorder (AUD) is a ubiquitous substance use disorder in the world, of which neural mechanisms remain unclear. Alcohol consumption induces neuro-adaptations in the dopaminergic system originating from the ventral tegmental area (VTA), an important brain region for the reward function in...

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Bibliographic Details
Main Authors: Xin-Xin Li, Tao Yang, Na Wang, Li-Li Zhang, Xing Liu, Yan-Min Xu, Qing Gao, Xiao-Feng Zhu, Yan-Zhong Guan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Neuroscience
Subjects:
7
8-Dihydroxyflavone
TrkB
BDNF
ventral tegmental area
alcohol-related behavior
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.00467/full

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https://www.frontiersin.org/article/10.3389/fnins.2020.00467/full

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