Utility of Maternal 6-Thioguanine Nucleotide Levels in Predicting Neonatal Pancytopenia

Abstract An infant with pancytopenia was born to a mother who used the common immunosuppressant azathioprine (AZA). Maternal and neonatal blood levels of 6-thioguanine nucleotides (6TGN; metabolite of AZA) were 1890 and 1480 pmol/8 × 108 red blood cells, respectively. Maternal 6TGN levels could be u...

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Bibliographic Details
Main Authors: Hidehiko Maruyama, Katsuhiko Tada, Takuzo Fujiwara, Kosuke Ota, Misao Kageyama
Format: Article
Language:English
Published: Thieme Medical Publishers, Inc. 2013-05-01
Series:American Journal of Perinatology Reports
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0032-1329683