Extracellular Vesicles Shed By Trypanosoma cruzi Potentiate Infection and Elicit Lipid Body Formation and PGE2 Production in Murine Macrophages

Extracellular Vesicles Shed By Trypanosoma cruzi Potentiate Infection and Elicit Lipid Body Formation and PGE2 Production in Murine Macrophages

During the onset of Trypanosoma cruzi infection, an effective immune response is necessary to control parasite replication and ensure host survival. Macrophages have a central role in innate immunity, acting as an important trypanocidal cell and triggering the adaptive immune response through antige...

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Bibliographic Details
Main Authors: Maria Isabel Lovo-Martins, Aparecida Donizette Malvezi, Nágela Ghabdan Zanluqui, Bruno Fernando Cruz Lucchetti, Vera Lúcia Hideko Tatakihara, Patricia Alves Mörking, Admilton Gonçalves de Oliveira, Samuel Goldenberg, Pryscilla Fanini Wowk, Phileno Pinge-Filho
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Immunology
Subjects:
extracellular vesicles
lipid bodies
macrophages
prostaglandin E2
Trypanosoma cruzi
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00896/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00896/full

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