ELOVL2 controls the level of n-6 28:5 and 30:5 fatty acids in testis, a prerequisite for male fertility and sperm maturation in mice

ELOVL2 is a member of the mammalian microsomal ELOVL fatty acid enzyme family, involved in the elongation of very long-chain fatty acids including PUFAs required for various cellular functions in mammals. Here, we used ELOVL2-ablated (Elovl2−/−) mice to show that the PUFAs with 24–30 carbon atoms of...

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Bibliographic Details
Main Authors: Damir Zadravec, Petr Tvrdik, Hervé Guillou, Richard Haslam, Tsutomu Kobayashi, Johnathan A. Napier, Mario R. Capecchi, Anders Jacobsson
Format: Article
Language:English
Published: Elsevier 2011-02-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752040519X