Antibodies Against Angiotensin II Receptor Type 1 and Endothelin A Receptor Are Associated With an Unfavorable COVID19 Disease Course

Antibodies Against Angiotensin II Receptor Type 1 and Endothelin A Receptor Are Associated With an Unfavorable COVID19 Disease Course

BackgroundLung histopathology demonstrates vasculopathy in a subset of deceased COVID19 patients, which resembles histopathology observed in antibody-mediated lung transplant rejection. Autoantibodies against angiotensin II type 1 receptor (AT1R) and Endothelin receptor Type A (ETAR) have been demon...

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Bibliographic Details
Main Authors: Jelle Miedema, Marco Schreurs, Simone van der Sar – van der Brugge, Marthe Paats, Sara Baart, Marleen Bakker, Rogier Hoek, Willem Arnout Dik, Henrik Endeman, Vincent Van Der Velden, Adriaan van Gammeren, Antonius Ermens, Joachim G. Aerts, Jan Von Der Thüsen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
COVID19
Endothelin Receptor Type A Antibody
Angiotensin II Receptor type 1 Antibody
Antinuclear antibody (ANA)
Autoimmunity
Prognosis (D011379)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.684142/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.684142/full

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