Molecular Functionality of Cytochrome P450 4 (CYP4) Genetic Polymorphisms and Their Clinical Implications

Molecular Functionality of Cytochrome P450 4 (CYP4) Genetic Polymorphisms and Their Clinical Implications

Enzymes in the cytochrome P450 4 (CYP4) family are involved in the metabolism of fatty acids, xenobiotics, therapeutic drugs, and signaling molecules, including eicosanoids, leukotrienes, and prostanoids. As CYP4 enzymes play a role in the maintenance of fatty acids and fatty-acid-derived bioactive...

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Bibliographic Details
Main Authors: Yazun Bashir Jarrar, Su-Jun Lee
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:International Journal of Molecular Sciences
Subjects:
<i>CYP4</i> genes
genetic polymorphisms
20-HETE
fatty acid
arachidonic acid
SNPs
molecular functionality
metabolism
lamellar ichthyosis
Bietti’s crystalline dystrophy
Online Access:https://www.mdpi.com/1422-0067/20/17/4274

Internet

https://www.mdpi.com/1422-0067/20/17/4274

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