Butyrate Inhibits Cancerous HCT116 Colon Cell Proliferation but to a Lesser Extent in Noncancerous NCM460 Colon Cells

Butyrate Inhibits Cancerous HCT116 Colon Cell Proliferation but to a Lesser Extent in Noncancerous NCM460 Colon Cells

Butyrate, an intestinal microbiota metabolite of dietary fiber, exhibits chemoprevention effects on colon cancer development. However, the mechanistic action of butyrate remains to be determined. We hypothesize that butyrate inhibits cancerous cell proliferation but to a lesser extent in noncancerou...

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Bibliographic Details
Main Authors: Huawei Zeng, David P. Taussig, Wen-Hsing Cheng, LuAnn K. Johnson, Reza Hakkak
Format: Article
Language:English
Published: MDPI AG 2017-01-01
Series:Nutrients
Subjects:
apoptosis
butyrate
colon cancer
cell proliferation
microbiota
Online Access:http://www.mdpi.com/2072-6643/9/1/25

Internet

http://www.mdpi.com/2072-6643/9/1/25

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