Simultaneous determination of candesartan and hydrochlorothiazide in human plasma by LC-MS/MS

Abstract A simple, sensitive, rapid and highly efficient LC-MS/MS method was developed for the determination of Candesartan and Hydrochlorothiazide simultaneously in human plasma. The method employed Zorbax eclipse C18 (150 X 4.6 mm, 5µ) column using acetate buffer: acetonitrile (25:75%, v/v) as the...

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Bibliographic Details
Main Authors: Mohan Gandhi Bonthu, Lakshmana Rao Atmakuri, Venkateswara Rao Jangala
Format: Article
Language:English
Published: Universidade de São Paulo 2018-06-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000100625&lng=en&tlng=en