Stereoselective one-pot synthesis of polypropionates

Polypropionates are present in many natural products possessing high bioactivity and therapeutic value. Here the authors show a strategy for the stereoselective assembly of polypropionates with three or four stereocentres through a process that includes a Diels–Alder reaction, silylenol ether hydrol...

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Bibliographic Details
Main Authors: Guo-Ming Ho, Medel Manuel L. Zulueta, Shang-Cheng Hung
Format: Article
Language:English
Published: Nature Publishing Group 2017-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-00787-y