Allele-Independent Turnover of Human Leukocyte Antigen (HLA) Class Ia Molecules.

Allele-Independent Turnover of Human Leukocyte Antigen (HLA) Class Ia Molecules.

Major histocompatibility complex class I (MHCI) glycoproteins present cytosolic peptides to CD8+ T cells and regulate NK cell activity. Their heavy chains (HC) are expressed from up to three MHC gene loci (human leukocyte antigen [HLA]-A, -B, and -C in humans), whose extensive polymorphism maps pred...

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Bibliographic Details
Main Authors: Claudia Prevosto, M Farooq Usmani, Sarah McDonald, Aleksandra M Gumienny, Tim Key, Reyna S Goodman, J S Hill Gaston, Michael J Deery, Robert Busch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0161011

Internet

https://doi.org/10.1371/journal.pone.0161011

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