Comparative genomic analysis of primary and synchronous metastatic colorectal cancers.

Approximately 50% of patients with primary colorectal carcinoma develop liver metastases. Understanding the genetic differences between primary colon cancer and their metastases to the liver is essential for devising a better therapeutic approach for this disease. We performed whole exome sequencing...

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Bibliographic Details
Main Authors: Sun Young Lee, Farhan Haq, Deokhoon Kim, Cui Jun, Hui-Jong Jo, Sung-Min Ahn, Won-Suk Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24599305/pdf/?tool=EBI