White matter tract integrity metrics reflect the vulnerability of late-myelinating tracts in Alzheimer's disease

White matter tract integrity metrics reflect the vulnerability of late-myelinating tracts in Alzheimer's disease

Post-mortem and imaging studies have observed that white matter (WM) degenerates in a pattern inverse to myelin development, suggesting preferential regional vulnerabilities influencing cognitive decline in AD. This study applied novel WM tract integrity (WMTI) metrics derived from diffusional kurto...

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Bibliographic Details
Main Authors: Andreana Benitez, Els Fieremans, Jens H. Jensen, Maria F. Falangola, Ali Tabesh, Steven H. Ferris, Joseph A. Helpern
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:NeuroImage: Clinical
Subjects:
White matter
Diffusional kurtosis imaging
Diffusion MRI
Verbal fluency
Alzheimer's disease
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158213001496

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http://www.sciencedirect.com/science/article/pii/S2213158213001496

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