Cell-Type-Specific Gene Programs of the Normal Human Nephron Define Kidney Cancer Subtypes

Cell-Type-Specific Gene Programs of the Normal Human Nephron Define Kidney Cancer Subtypes

Comprehensive transcriptome studies of cancers often rely on corresponding normal tissue samples to serve as a transcriptional reference. In this study, we performed in-depth analyses of normal kidney tissue transcriptomes from the TCGA and demonstrate that the histological variability in cellularit...

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Bibliographic Details
Main Authors: David Lindgren, Pontus Eriksson, Krzysztof Krawczyk, Helén Nilsson, Jennifer Hansson, Srinivas Veerla, Jonas Sjölund, Mattias Höglund, Martin E. Johansson, Håkan Axelson
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:Cell Reports
Subjects:
kidney
nephron
gene expression
renal cell carcinoma
RCC
cell of origin
HIF
NHF
FOXI1
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717310227

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http://www.sciencedirect.com/science/article/pii/S2211124717310227

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