IMPAIRED NEOVASCULARIZATION AND REDUCED CAPILLARY SUPPLY IN THE MALIGNANT VERSUS NON-MALIGNANT COURSE OF EXPERIMENTAL RENOVASCULAR HYPERTENSION

IMPAIRED NEOVASCULARIZATION AND REDUCED CAPILLARY SUPPLY IN THE MALIGNANT VERSUS NON-MALIGNANT COURSE OF EXPERIMENTAL RENOVASCULAR HYPERTENSION

Malignant hypertension develops in some cases of hypertension but not in others. We hypothesized that an impaired neovascularization and a reduced capillary supply characterizes the malignant course of experimental hypertension. Two-kidney, one-clip renovascular hypertension was induced in rats; con...

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Bibliographic Details
Main Authors: Andrea Hartner, Lisa Jagusch, Nada Cordasic, Kerstin Amann, Roland Veelken, Johannes Jacobi, Karl F. Hilgers
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Physiology
Subjects:
Aldosterone
VEGF
Angiogenesis
neovascularization
PAI-1
malignant hypertension
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00370/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00370/full

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