Human cerebrospinal fluid promotes neuronal viability and activity of hippocampal neuronal circuits in vitro

Human cerebrospinal fluid promotes neuronal viability and activity of hippocampal neuronal circuits in vitro

For decades it has been hypothesized that molecules within the cerebrospinal fluid (CSF) diffuse into the brain parenchyma and influence the function of neurons. However, the functional consequences of CSF on neuronal circuits are largely unexplored and unknown. A major reason for this is the absenc...

Full description

Bibliographic Details
Main Authors: Marta ePerez-Alcazar, Georgia eCulley, Tim eLyckenvik, Kristoffer eMobarrez, Andreas eBjorefeldt, Pontus eWasling, Henrik eSeth, Fredrik eAsztely, Andrea eHarrer, Bernhard eIglseder, Ludwig eAigner, Eric eHanse, Sebastian eIlles
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-03-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Human cerebrospinal fluid
Organotypic hippocampal slice cultures
hippocampal neuronal function
hippocampal neuronal survival
hippocampal neuronal cultures
multi-electrode array technology
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2016.00054/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2016.00054/full

Similar Items