Effect of crude extract and its semi purified constituents from guaraná seeds [Paullinia cupana var. sorbilis (Mart.) lucke] on cognitive performance in Morris water maze in rats

Effect of crude extract and its semi purified constituents from guaraná seeds [Paullinia cupana var. sorbilis (Mart.) lucke] on cognitive performance in Morris water maze in rats

The effect of crude lyophilized extract (EBPC) and the semi-purified constituents (EPA and EPB) of Paullinia cupana (guaraná) seeds long-term administered in rats by gavage at different doses was studied on cognitive behavior in rats. EBPC (30.0 mg/kg) and EPA (2.0 mg/kg), but not EPB (2.0 or 4.0 mg...

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Bibliographic Details
Main Authors: Fernanda Jacques Otobone, Andréia Conegero Sanches, Rosangela Lika Nagae, Juliana Vanessa Colombo Martins, Simoni Obici, João Carlos Palazzo de Mello, Elisabeth Aparecida Audi
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 2005-09-01
Series:Brazilian Archives of Biology and Technology
Subjects:
Cognitive effects
guaraná
Morris water maze
Paullinia cupana
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000600007

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000600007

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