circZNF827 nucleates a transcription inhibitory complex to balance neuronal differentiation

circZNF827 nucleates a transcription inhibitory complex to balance neuronal differentiation

Circular RNAs are important for many cellular processes but their mechanisms of action remain poorly understood. Here, we map circRNA inventories of mouse embryonic stem cells, neuronal progenitor cells and differentiated neurons and identify hundreds of highly expressed circRNAs. By screening sever...

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Bibliographic Details
Main Authors: Anne Kruse Hollensen, Henriette Sylvain Thomsen, Marta Lloret-Llinares, Andreas Bjerregaard Kamstrup, Jacob Malte Jensen, Majbritt Luckmann, Nanna Birkmose, Johan Palmfeldt, Torben Heick Jensen, Thomas B Hansen, Christian Kroun Damgaard
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-11-01
Series:eLife
Subjects:
circular RNA
neuronal differentiation
gene expression
RNA-binding proteins
transcriptional regulation
Online Access:https://elifesciences.org/articles/58478

Internet

https://elifesciences.org/articles/58478

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