Xanthones from the Leaves of Garcinia cowa Induce Cell Cycle Arrest, Apoptosis, and Autophagy in Cancer Cells

Xanthones from the Leaves of Garcinia cowa Induce Cell Cycle Arrest, Apoptosis, and Autophagy in Cancer Cells

Two new xanthones, cowaxanthones G (1) and H (2), and 23 known analogues were isolated from an acetone extract of the leaves of Garcinia cowa. The isolated compounds were evaluated for cytotoxicity against three cancer cell lines and immortalized HL7702 normal liver cells, whereby compounds 1, 5, 8,...

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Bibliographic Details
Main Authors: Zhengxiang Xia, Hong Zhang, Danqing Xu, Yuanzhi Lao, Wenwei Fu, Hongsheng Tan, Peng Cao, Ling Yang, Hongxi Xu
Format: Article
Language:English
Published: MDPI AG 2015-06-01
Series:Molecules
Subjects:
Garcinia cowa
xanthone
cytotoxicity
apoptosis
cell cycle arrest
autophagy
Online Access:http://www.mdpi.com/1420-3049/20/6/11387

Internet

http://www.mdpi.com/1420-3049/20/6/11387

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