Environmental Stimulation Counteracts the Suppressive Effects of Maternal High-Fructose Diet on Cell Proliferation and Neuronal Differentiation in the Dentate Gyrus of Adult Female Offspring via Histone Deacetylase 4

Environmental Stimulation Counteracts the Suppressive Effects of Maternal High-Fructose Diet on Cell Proliferation and Neuronal Differentiation in the Dentate Gyrus of Adult Female Offspring via Histone Deacetylase 4

Maternal high-fructose diets (HFD) impair the learning and memory capacity of adult female offspring via histone deacetylase 4 (HDAC4). Hippocampal adult neurogenesis is important for supporting the function of existing neural circuits. In this study, we investigated the effects of maternal HFD on h...

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Bibliographic Details
Main Authors: Wen-Chung Liu, Chih-Wei Wu, Pi-Lien Hung, Julie Y. H. Chan, You-Lin Tain, Mu-Hui Fu, Lee-Wei Chen, Chih-Kuang Liang, Chun-Ying Hung, Hong-Ren Yu, I-Chun Chen, Kay L.H. Wu
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Environmental Research and Public Health
Subjects:
maternal high-fructose diet
neural stem cell proliferation
neuronal differentiation
histone deacetylase 4
enriched housing
Online Access:https://www.mdpi.com/1660-4601/17/11/3919

Internet

https://www.mdpi.com/1660-4601/17/11/3919

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