LXYL-P1-2 immobilized on magnetic nanoparticles and its potential application in paclitaxel production

LXYL-P1-2 immobilized on magnetic nanoparticles and its potential application in paclitaxel production

Background: LXYL-P1-2 is the first reported glycoside hydrolase that can catalyze the transformation of 7-β-xylosyl-10-deacetyltaxol (XDT) to 10-deacetyltaxol (DT) by removing the d-xylosyl group at the C-7 position. Successful synthesis of paclitaxel by one-pot method combining the LXYL-P1-2 and 10...

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Bibliographic Details
Main Authors: Sen Zou, Tian-Jiao Chen, Dan-Yang Li, Shuai Fan, Zhao-Yong Yang, Ping Zhu
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Electronic Journal of Biotechnology
Subjects:
10-Deacetyltaxol
7-β-Xylosyltaxane glycoside hydrolases
Enzyme kinetics
Glycoside hydrolase
Immobilization
Industrial production
Online Access:http://www.sciencedirect.com/science/article/pii/S0717345820300658

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http://www.sciencedirect.com/science/article/pii/S0717345820300658

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