Female mice exposed to low doses of dioxin during pregnancy and lactation have increased susceptibility to diet-induced obesity and diabetes

Female mice exposed to low doses of dioxin during pregnancy and lactation have increased susceptibility to diet-induced obesity and diabetes

Objective: Exposure to persistent organic pollutants is consistently associated with increased diabetes risk in humans. We investigated the short- and long-term impact of transient low-dose dioxin (2,3,7,8-tetrachlorodibenzo-p-dioxin, TCDD) exposure during pregnancy and lactation on glucose homeosta...

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Bibliographic Details
Main Authors: Myriam P. Hoyeck, Rayanna C. Merhi, Hannah L. Blair, C. Duncan Spencer, Mikayla A. Payant, Diana I. Martin Alfonso, Melody Zhang, Geronimo Matteo, Melissa J. Chee, Jennifer E. Bruin
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Molecular Metabolism
Subjects:
Beta cells
Diabetes
Dioxin
Metabolic plasticity
Obesity
Pregnancy
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877820301782

Internet

http://www.sciencedirect.com/science/article/pii/S2212877820301782

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