Distinct molecular subtypes of uterine leiomyosarcoma respond differently to chemotherapy treatment

Distinct molecular subtypes of uterine leiomyosarcoma respond differently to chemotherapy treatment

Abstract Background Uterine leiomyosarcoma (ULMS) is an aggressive form of soft tissue tumors. The molecular heterogeneity and pathogenesis of ULMS are not well understood. Methods Expression profiling data were used to determine the possibility and optimal number of ULMS molecular subtypes. Next, c...

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Bibliographic Details
Main Authors: Yang An, Shuzhen Wang, Songlin Li, Lulu Zhang, Dayong Wang, Haojie Wang, Shibai Zhu, Wan Zhu, Yongqiang Li, Wenwu Chen, Shaoping Ji, Xiangqian Guo
Format: Article
Language:English
Published: BMC 2017-09-01
Series:BMC Cancer
Subjects:
Uterine leiomyosarcoma
Molecular subtype
Molecular signature
Gene expression pattern
Subtype-specific treatment
Online Access:http://link.springer.com/article/10.1186/s12885-017-3568-y

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http://link.springer.com/article/10.1186/s12885-017-3568-y

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