The Synergistic Effects of 5-Aminosalicylic Acid and Vorinostat in the Treatment of Ulcerative Colitis

The Synergistic Effects of 5-Aminosalicylic Acid and Vorinostat in the Treatment of Ulcerative Colitis

Background: The drug 5-aminosalicylic acid (5-ASA) is the first-line therapy for the treatment of patients with mild-to-moderate ulcerative colitis (UC). However, in some cases, 5-ASA cannot achieve the desired therapeutic effects. Therefore, patients have to undergo therapies that include corticost...

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Bibliographic Details
Main Authors: Long He, Shuting Wen, Zhuotai Zhong, Senhui Weng, Qilong Jiang, Hong Mi, Fengbin Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Pharmacology
Subjects:
ulcerative colitis
5-ASA
SAHA
protein-metabolite interactions
butyric acid
synergistic effects
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.625543/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.625543/full

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