Cell Sorting and Noise-Induced Cell Plasticity Coordinate to Sharpen Boundaries between Gene Expression Domains.

A fundamental question in biology is how sharp boundaries of gene expression form precisely in spite of biological variation/noise. Numerous mechanisms position gene expression domains across fields of cells (e.g. morphogens), but how these domains are refined remains unclear. In some cases, domain...

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Bibliographic Details
Main Authors: Qixuan Wang, William R Holmes, Julian Sosnik, Thomas Schilling, Qing Nie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5279720?pdf=render