Enhanced uptake of potassium or glycine betaine or export of cyclic-di-AMP restores osmoresistance in a high cyclic-di-AMP Lactococcus lactis mutant.

Enhanced uptake of potassium or glycine betaine or export of cyclic-di-AMP restores osmoresistance in a high cyclic-di-AMP Lactococcus lactis mutant.

The broadly conserved bacterial signalling molecule cyclic-di-adenosine monophosphate (c-di-AMP) controls osmoresistance via its regulation of potassium (K+) and compatible solute uptake. High levels of c-di-AMP resulting from inactivation of c-di-AMP phosphodiesterase activity leads to poor growth...

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Bibliographic Details
Main Authors: Huong Thi Pham, Nguyen Thi Hanh Nhiep, Thu Ngoc Minh Vu, TuAnh Ngoc Huynh, Yan Zhu, Anh Le Diep Huynh, Alolika Chakrabortti, Esteban Marcellin, Raquel Lo, Christopher B Howard, Nidhi Bansal, Joshua J Woodward, Zhao-Xun Liang, Mark S Turner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-08-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC6108528?pdf=render

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http://europepmc.org/articles/PMC6108528?pdf=render

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