Effects of Ranibizumab and Aflibercept on Human Müller Cells and Photoreceptors under Stress Conditions

Effects of Ranibizumab and Aflibercept on Human Müller Cells and Photoreceptors under Stress Conditions

Anti-vascular endothelial growth factor (VEGF) therapy has revolutionized the treatment of retinal vascular diseases. However, constitutive VEGF also acts as a trophic factor on retinal nonvascular cells. We have studied the effects of aflibercept and ranibizumab on human Müller cells and photorecep...

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Bibliographic Details
Main Authors: Weiyong Shen, Belinda Yau, So-Ra Lee, Ling Zhu, Michelle Yam, Mark C. Gillies
Format: Article
Language:English
Published: MDPI AG 2017-03-01
Series:International Journal of Molecular Sciences
Subjects:
vascular endothelial growth factor
aflibercept
ranibizumab
Müller cells
photoreceptors
neurotrophic factors
heat shock proteins
redox proteins
interphotoreceptor retinoid-binding protein
Online Access:http://www.mdpi.com/1422-0067/18/3/533

Internet

http://www.mdpi.com/1422-0067/18/3/533

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