Predicting HIV-1 Protease Cleavage Sites With Positive-Unlabeled Learning

Understanding the substrate specificity of HIV-1 protease plays an essential role in the prevention of HIV infection. A variety of computational models have thus been developed to predict substrate sites that are cleaved by HIV-1 protease, but most of them normally follow a supervised learning schem...

Full description

Bibliographic Details
Main Authors: Zhenfeng Li, Lun Hu, Zehai Tang, Cheng Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.658078/full