Transcriptome Analysis Reveals Downregulation of Urocortin Expression in the Hypothalamo-Neurohypophysial System of Spontaneously Hypertensive Rats

Transcriptome Analysis Reveals Downregulation of Urocortin Expression in the Hypothalamo-Neurohypophysial System of Spontaneously Hypertensive Rats

The chronically increased blood pressure characteristic of essential hypertension represents an insidious and cumulative risk for cardiovascular disease. Essential hypertension is a multifactorial condition, with no known specific aetiology but a strong genetic component. The Spontaneously Hypertens...

Full description

Bibliographic Details
Main Authors: Andrew Martin, Andre S. Mecawi, Vagner R. Antunes, Song T. Yao, Jose Antunes-Rodrigues, Julian F. R. Paton, Alex Paterson, Michael Greenwood, Olivera Šarenac, Bojana Savić, Nina Japundžić-Žigon, David Murphy, Charles C. T. Hindmarch
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Physiology
Subjects:
hypothalamo-neurohypophyseal system
transcriptome
SHR
UCN
spectral analysis
microarray
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2020.599507/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2020.599507/full

Similar Items