Identification of a super-functional Tfh-like subpopulation in murine lupus by pattern perception

Identification of a super-functional Tfh-like subpopulation in murine lupus by pattern perception

Dysregulated cytokine expression by T cells plays a pivotal role in the pathogenesis of autoimmune diseases. However, the identification of the corresponding pathogenic subpopulations is a challenge, since a distinction between physiological variation and a new quality in the expression of protein m...

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Bibliographic Details
Main Authors: Stefanie Gryzik, Yen Hoang, Timo Lischke, Elodie Mohr, Melanie Venzke, Isabelle Kadner, Josephine Poetzsch, Detlef Groth, Andreas Radbruch, Andreas Hutloff, Ria Baumgrass
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-05-01
Series:eLife
Subjects:
autoimmune disease
cytokine expression
multi-parametric analysis
combinatorial protein expression
cd4+ t cells
high-dimensional flow cytometry
Online Access:https://elifesciences.org/articles/53226

Internet

https://elifesciences.org/articles/53226

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