Behavioral characterization of the hyperphagia synphilin-1 overexpressing mice.

Synphilin-1 is a cytoplasmic protein that has been shown to be involved in the control of energy balance. Previously, we reported on the generation of a human synphilin-1 transgenic mouse model (SP1), in which overexpression of human synphilin-1 resulted in hyperphagia and obesity. Here, behavioral...

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Bibliographic Details
Main Authors: Xueping Li, Yada Treesukosol, Alexander Moghadam, Megan Smith, Erica Ofeldt, Dejun Yang, Tianxia Li, Kellie Tamashiro, Pique Choi, Timothy H Moran, Wanli W Smith
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4020742?pdf=render