Thymoquinone Inhibits the Migration and Invasive Characteristics of Cervical Cancer Cells SiHa and CaSki In Vitro by Targeting Epithelial to Mesenchymal Transition Associated Transcription Factors Twist1 and Zeb1

Thymoquinone Inhibits the Migration and Invasive Characteristics of Cervical Cancer Cells SiHa and CaSki In Vitro by Targeting Epithelial to Mesenchymal Transition Associated Transcription Factors Twist1 and Zeb1

Cervical cancer is one of the most common gynecological malignant tumors worldwide, for which chemotherapeutic strategies are limited due to their non-specific cytotoxicity and drug resistance. The natural product thymoquinone (TQ) has been reported to target a vast number of signaling pathways in c...

Full description

Bibliographic Details
Main Authors: Jun Li, Md. Asaduzzaman Khan, Chunli Wei, Jingliang Cheng, Hanchun Chen, Lisha Yang, Iqra Ijaz, Junjiang Fu
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Molecules
Subjects:
thymoquinone
cervical cancer
metastasis
epithelial to mesenchymal transition
Twist1
Zeb1
E-Cadherin
Online Access:https://www.mdpi.com/1420-3049/22/12/2105

Internet

https://www.mdpi.com/1420-3049/22/12/2105

Similar Items