Measurement of hydroxychloroquine in blood from SLE patients using LC-HRMS—evaluation of whole blood, plasma, and serum as sample matrices

Abstract Background Hydroxychloroquine (HCQ) is the standard of care in the treatment of systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), and other inflammatory rheumatic diseases and potentially for the treatment in COVID-19 patients. Determination of HCQ for therapeutic drug monitori...

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Bibliographic Details
Main Authors: Henrik Carlsson, Karin Hjorton, Sandy Abujrais, Lars Rönnblom, Torbjörn Åkerfeldt, Kim Kultima
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Arthritis Research & Therapy
Online Access:http://link.springer.com/article/10.1186/s13075-020-02211-1