The Dualistic Effect of COX-2-Mediated Signaling in Obesity and Insulin Resistance

The Dualistic Effect of COX-2-Mediated Signaling in Obesity and Insulin Resistance

Obesity and insulin resistance are two major risk factors for the development of metabolic syndrome, type 2 diabetes and associated cardiovascular diseases (CVDs). Cyclooxygenase (COX), a rate-limiting enzyme responsible for the biosynthesis of prostaglandins (PGs), exists in two isoforms: COX-1, th...

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Bibliographic Details
Main Authors: Pei-Chi Chan, Min-Tser Liao, Po-Shiuan Hsieh
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:International Journal of Molecular Sciences
Subjects:
cyclooxygenase II
prostaglandins
obesity
metabolic syndrome
energy metabolism
Online Access:https://www.mdpi.com/1422-0067/20/13/3115

Internet

https://www.mdpi.com/1422-0067/20/13/3115

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