Key Players in HIV-1 Transcriptional Regulation: Targets for a Functional Cure

HIV-1 establishes a life-long infection when proviral DNA integrates into the host genome. The provirus can then either actively transcribe RNA or enter a latent state, without viral production. The switch between these two states is governed in great part by the viral protein, Tat, which promotes R...

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Bibliographic Details
Main Authors: Luisa Mori, Susana T. Valente
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/12/5/529