Key Players in HIV-1 Transcriptional Regulation: Targets for a Functional Cure
HIV-1 establishes a life-long infection when proviral DNA integrates into the host genome. The provirus can then either actively transcribe RNA or enter a latent state, without viral production. The switch between these two states is governed in great part by the viral protein, Tat, which promotes R...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-05-01
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Series: | Viruses |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4915/12/5/529 |