MicroRNA-18a-5p Administration Suppresses Retinal Neovascularization by Targeting FGF1 and HIF1A

MicroRNA-18a-5p Administration Suppresses Retinal Neovascularization by Targeting FGF1 and HIF1A

Pathologic ocular neovascularization commonly results in visual impairment or even blindness in numerous fundus diseases, including proliferative diabetic retinopathy (PDR), retinopathy of prematurity (ROP), and age-related macular degeneration (AMD). MicroRNAs regulate angiogenesis through modulati...

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Bibliographic Details
Main Authors: Ji-Tian Guan, Xin-Xin Li, De-Wei Peng, Wen-Meng Zhang, Jia Qu, Fan Lu, Robert J. D’Amato, Zai-Long Chi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Pharmacology
Subjects:
miR-18a-5p
neovascularization
proliferative retinopathy
FGF1
HIF1A
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00276/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.00276/full

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