T Cell Activation Machinery: Form and Function in Natural and Engineered Immune Receptors

T Cell Activation Machinery: Form and Function in Natural and Engineered Immune Receptors

The impressive success of chimeric antigen receptor (CAR)-T cell therapies in treating advanced B-cell malignancies has spurred a frenzy of activity aimed at developing CAR-T therapies for other cancers, particularly solid tumors, and optimizing engineered T cells for maximum clinical benefit in man...

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Bibliographic Details
Main Authors: Nicholas J. Chandler, Melissa J. Call, Matthew E. Call
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
T cell
immunoreceptor
CAR
structure
chimeric antigen receptor
Online Access:https://www.mdpi.com/1422-0067/21/19/7424

Internet

https://www.mdpi.com/1422-0067/21/19/7424

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