Oligonucleotide Functionalised Microbeads: Indispensable Tools for High-Throughput Aptamer Selection

Oligonucleotide Functionalised Microbeads: Indispensable Tools for High-Throughput Aptamer Selection

The functionalisation of microbeads with oligonucleotides has become an indispensable technique for high-throughput aptamer selection in SELEX protocols. In addition to simplifying the separation of binding and non-binding aptamer candidates, microbeads have facilitated the integration of other tech...

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Bibliographic Details
Main Authors: Lewis A. Fraser, Andrew B. Kinghorn, Marco S. L. Tang, Yee-Wai Cheung, Bryce Lim, Shaolin Liang, Roderick M. Dirkzwager, Julian A. Tanner
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:Molecules
Subjects:
aptamer
SELEX
microbead
monoclonal bead
ePCR
FACS
Online Access:http://www.mdpi.com/1420-3049/20/12/19766

Internet

http://www.mdpi.com/1420-3049/20/12/19766

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