TNF neutralization results in the delay of transplantable tumor growth and reduced MDSC accumulation.

TNF neutralization results in the delay of transplantable tumor growth and reduced MDSC accumulation.

Myeloid-derived suppressor cells (MDSC) represent a heterogeneous population of immature myeloid cells that under normal conditions may differentiate into mature macrophages, granulocytes and dendritic cells. However, under pathological conditions associated with inflammation, cancer or infection su...

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Bibliographic Details
Main Authors: Kamar-Sulu N. Atretkhany, Maxim A. Nosenko, Violetta S. Gogoleva, Ruslan V. Zvartsev, Zhihai eQin, Sergei A. Nedospasov, Marina S. Drutskaya
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-04-01
Series:Frontiers in Immunology
Subjects:
Pro-inflammatory cytokines
TNF
IL-6
MDSC
Anti-cytokine therapy
transplantable tumor model
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00147/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00147/full

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