Evidence of the Cellular Senescence Stress Response in Mitotically Active Brain Cells—Implications for Cancer and Neurodegeneration

Cellular stress responses influence cell fate decisions. Apoptosis and proliferation represent opposing reactions to cellular stress or damage and may influence distinct health outcomes. Clinical and epidemiological studies consistently report inverse comorbidities between age-associated neurodegene...

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Bibliographic Details
Main Authors: Gregory J. Gillispie, Eric Sah, Sudarshan Krishnamurthy, Mohamed Y. Ahmidouch, Bin Zhang, Miranda E. Orr
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/11/2/153