Lipase-catalysed sequential kinetic resolution of α-lipoic acid

Lipase from Aspergillus sp. WZ002 was employed to kinetically resolve racemicα-lipoic acid by a sequential esterification process. Though the remoteness of this substrate’sstereocentre from the reaction centre provided a significant challenge, the introduction ofsequential kinetic resolution dramati...

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Bibliographic Details
Main Author: Zhao Wang
Format: Article
Language:English
Published: Maejo University 2012-04-01
Series:Maejo International Journal of Science and Technology
Subjects:
Online Access:http://www.mijst.mju.ac.th/vol6/152-158.pdf