Lipase-catalysed sequential kinetic resolution of α-lipoic acid
Lipase from Aspergillus sp. WZ002 was employed to kinetically resolve racemicα-lipoic acid by a sequential esterification process. Though the remoteness of this substrate’sstereocentre from the reaction centre provided a significant challenge, the introduction ofsequential kinetic resolution dramati...
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Format: | Article |
Language: | English |
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Maejo University
2012-04-01
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Series: | Maejo International Journal of Science and Technology |
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Online Access: | http://www.mijst.mju.ac.th/vol6/152-158.pdf |