treeclimbR pinpoints the data-dependent resolution of hierarchical hypotheses

Abstract treeclimbR is for analyzing hierarchical trees of entities, such as phylogenies or cell types, at different resolutions. It proposes multiple candidates that capture the latent signal and pinpoints branches or leaves that contain features of interest, in a data-driven way. It outperforms cu...

Full description

Bibliographic Details
Main Authors: Ruizhu Huang, Charlotte Soneson, Pierre-Luc Germain, Thomas S.B. Schmidt, Christian Von Mering, Mark D. Robinson
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Genome Biology
Online Access:https://doi.org/10.1186/s13059-021-02368-1