BMP9 protects septal neurons from axotomy-evoked loss of cholinergic phenotype.

Cholinergic projection from the septum to the hippocampus is crucial for normal cognitive function and degeneration of cells and nerve fibers within the septohippocampal pathway contributes to the pathophysiology of Alzheimer's disease. Bone morphogenetic protein (BMP) 9 is a cholinergic differ...

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Bibliographic Details
Main Authors: Ignacio Lopez-Coviella, Tiffany J Mellott, Aletta C Schnitzler, Jan K Blusztajn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3113905?pdf=render