Silibinin improves palmitate-induced insulin resistance in C2C12 myotubes by attenuating IRS-1/PI3K/Akt pathway inhibition

The present study investigated the effect of silibinin, the principal potential anti-inflammatory flavonoid contained in silymarin, a mixture of flavonolignans extracted from Silybum marianum seeds, on palmitate-induced insulin resistance in C2C12 myotubes and its potential molecular mechanisms. Sil...

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Bibliographic Details
Main Authors: H.B. Li, Y.R.Y. Yang, Z.J. Mo, Y. Ding, W.J. Jiang
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2015-05-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015000500440&lng=en&tlng=en