A new approach for potential drug target discovery through in silico metabolic pathway analysis using Trypanosoma cruzi genome information

A new approach for potential drug target discovery through in silico metabolic pathway analysis using Trypanosoma cruzi genome information

The current drug options for the treatment of chronic Chagas disease have not been sufficient and high hopes have been placed on the use of genomic data from the human parasite Trypanosoma cruzi to identify new drug targets and develop appropriate treatments for both acute and chronic Chagas disease...

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Bibliographic Details
Main Authors: Marcelo Alves-Ferreira, Ana Carolina Ramos Guimarães, Priscila Vanessa da Silva Zabala Capriles, Laurent E Dardenne, Wim M Degrave
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2009-12-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Trypanosoma cruzi
metabolism
metabolic pathways
drug target
analogous enzyme
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762009000800006

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762009000800006

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