Cilia-Associated Genes Play Differing Roles in Aminoglycoside-Induced Hair Cell Death in Zebrafish

Cilia-Associated Genes Play Differing Roles in Aminoglycoside-Induced Hair Cell Death in Zebrafish

Hair cells possess a single primary cilium, called the kinocilium, early in development. While the kinocilium is lost in auditory hair cells of most species it is maintained in vestibular hair cells. It has generally been believed that the primary role of the kinocilium and cilia-associated genes in...

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Bibliographic Details
Main Authors: Tamara M. Stawicki, Liana Hernandez, Robert Esterberg, Tor Linbo, Kelly N. Owens, Arish N. Shah, Nihal Thapa, Brock Roberts, Cecilia B. Moens, Edwin W. Rubel, David W. Raible
Format: Article
Language:English
Published: Oxford University Press 2016-07-01
Series:G3: Genes, Genomes, Genetics
Subjects:
aminoglycosides
cilia
hair cells
intraflagellar transport
transition zone
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.116.030080

Internet

http://g3journal.org/lookup/doi/10.1534/g3.116.030080

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